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No specific dose adjustment proposed when tofacitinib coadministered with powerful CYP2C19 inhibitors; lower tofacitinib dose if coadministered with the two reasonable CYP3A4 and powerful CYP2C19 inhibitors .posaconazole will raise the stage or impact of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.Stay

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